Fig. 3

TAD analysis in response to nitrogen deprivation in N. oceanica. A TAD of chromosome 3 as an example exhibited under C0, N1 and N2. Blue and dark-red represented TAD border and inter, respectively. B Venn diagram of TAD under C0, N1 and N2, respectively. C The number of genes in the regions of TAD border and inter identified under C0, N1 and N2. Blue and dark-red represented TAD border and inter, respectively. D The transition of TAD in response to nitrogen deprivation under C0 vs. N1, C0 vs. N2, and N1 vs. N2. TAD transition was firstly defined as four types including ‘Stable’ (the overlapped proportion of the TAD in two treatments was above 0.75), ‘Split’ (one TAD divided into two or more TADs), ‘Merge’ (two or more TADs fused into one TAD), and ‘Rearrangement’ (remaining situations) [36]. E The gene expression level of TAD border and inter analyzed under C0, N1, and N2. Blue and dark-red represented TAD border and inter, respectively