Fig. 3

Model-predicted vs. actual fermentation of a glucose-xylose mixture by A. tubingensis. Dynamic FBA was conducted using the reconstructed genome-scale metabolic model to simulate the sequential uptake of glucose and xylose. The solid lines represent the simulation results from the dFBA run for biomass (A), phosphate (B), citric acid (C), glucose (D) and xylose (E). Experimentally, A. tubingensis DJU120 strain was used to ferment a mixture of glucose (80 g/L) and xylose (40 g/L). The dots and the associated error bars represent the experimental data ± s.d. from (n = 3) different runs