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Fig. 1 | Biotechnology for Biofuels and Bioproducts

Fig. 1

From: Combining transcriptomic and metabolomic insights into carbohydrate utilization by Ruminiclostridium papyrosolvens DSM2782

Fig. 1

Growth and gene expression of R. papyrosolvens under various carbon sources. A Growth curves of R. papyrosolvens cultured on 3 g/L glucose, cellobiose, xylan, cellulose, and corn stover. Error bars indicate the standard deviation of the three replicates. B Principal component analysis of transcriptomic samples. The color of the scatter plots represents the grouping of samples. C Venn diagram of the distribution of the encoding genes expressed as mean FPKM (calculated on 3 biological replicates) values among glucose, cellobiose, xylan, cellulose, and corn stover. D Functional annotation of total genes annotated in the genome (Total) and common genes expressed under five carbon sources (Common). Number of the genes in each COG term are shown in columns (D, cell cycle control, cell division, chromosome partitioning; J, translation, ribosomal structure and biogenesis; N, cell motility; O, posttranslational modification, protein turnover, chaperones; A, RNA processing and modification; B, chromatin structure and dynamics; C, energy production and conversion; E, amino acid transport and metabolism; F, nucleotide transport and metabolism; G, carbohydrate transport and metabolism; H, coenzyme transport and metabolism; I, lipid transport and metabolism; K, transcription; L, replication, recombination and repair; M, cell wall/membrane/envelope biogenesis; P, inorganic ion transport and metabolism; Q, secondary metabolites biosynthesis, transport and catabolism; S, function unknown; T, signal transduction mechanisms; U, intracellular trafficking, secretion, and vesicular transport; V, defense mechanisms; Z, cytoskeleton). Genes identified were enriched in D, J, N, and O of COG categories (*P < 0.01, hypergeometric test)

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