Fig. 4

Morphological modifications of WT and hpCAD vessels subjected to DAP on a 2D section of the 3D scan. A Evolution of the relative surface area occupied by the vessels; B evolution of the distribution of the Feret diameter ratios of the vessels, a proxy of cell deformation. The first quartile Q1 is the lower limit of the box, the dotted and solid lines inside the box indicate the mean and the median, respectively, and the third quartile Q3 is the upper limit of the box. The low mustache with the dots below represents the first decile and the lowest 10% of values, and the high mustache with the dots above represents the ninth decile and the highest 10% of values. C Representation of the deformation of whole vessels on 2D sections. Depending on the samples, the number of vessels identified on the standard surface area varies from 17 to 86